The only way to treat a macular hole is by having an operation. Eye drops or glasses are ineffective.
An alternative to surgery is a new therapy called ocriplasmin which is a drug injected into the eye. Although an initial study has shown that this treatment may be beneficial in selected cases, it is still undergoing clinical assessment. Generally, it is not as reliable as surgery and the majority of patients treated with ocriplasmin will go on to have surgery. This option can be discussed with your consultant.
Some patients decide not to have an operation and accept the poor central vision in the affected eye. This is reasonable, especially if the vision in the other eye is not affected. There is no “right” or “wrong” decision as every person has different needs and priorities.
You should discuss your reasons for wanting to proceed with an operation or for deciding not to have surgery with your consultant.
The success rate of macular hole surgery – a vitrectomy – depends on many factors, and you should discuss these with your eye doctor. Overall, there is about a 90% chance of “closing” the macular hole. Nevertheless, there is a small chance that your vision may not improve after surgery, even if the hole is “closed”. Surgery for macular hole repairs is generally very safe. However, there are risks and consequences:
Most operations for macular holes are performed under a local anaesthetic, which means you will be awake throughout your operation. We will inject local anaesthetic into the area around your eye to numb your eye and prevent you from feeling any pain during the operation. You will not be able to see details of what is happening, but you might be aware of the bright lights or movement in the operating theatre. During the operation, we will ask you to lie as flat as possible and keep your head still.
General anaesthesia, under which you are asleep for the whole operation, is rarely used for macular hole surgery. If you require a general anaesthetic, you will need to follow specific instructions about eating and drinking prior to your operation.
The operation to repair your macular hole is called a vitrectomy and usually takes about an hour. Whichever form of anaesthetic you chose, we will give you eye drops before your operation to enlarge your pupils. The surgeon will then make tiny openings in your eye and remove the vitreous (the jelly-like substance) from inside. Your eye is then filled with a bubble of special gas, which presses against the macula and seals the hole.
If we put a gas or air bubble in your eye you must not fly for the periods of time specified below. This is because the gas or air bubble will expand in size and can lead to raised pressure inside your eye, leading to visual loss.
We use three types of gases:
You will be told after your surgery which type of gas bubble was used. The surgeon might put small stitches in your eye to close up the opening. The stitches dissolve naturally over about four to six weeks. At the end of the operation, we usually put a pad and shield over your eye to protect it. These will be removed the morning after your surgery.
Your eye will feel uncomfortable, gritty, and itchy. It might appear red or bruised and the vision is likely to be very poor at first. This is normal for seven to 14 days. We will give you eye drops to reduce inflammation and to prevent infection, and will explain how and when you should use them. You can also take paracetamol for pain relief as advised on the packet. Please do not rub your eye. Your eye will take between two and six weeks to heal, but your vision might continue to improve for several months.
Your vision will be very poor with the gas in your eye. As the gas disperses and is replaced by your eye’s natural fluid, you will begin to see a line, which wobbles in your vision, like a spirit level. You will be able to see above the line, but the vision will be fuzzy underneath. This line will continue to ease downwards until only a tiny bubble is left and finally, it too will disappear.
It is important to note that the gas can react with another gas called nitrous oxide, which can cause problems in your eye if any is administered. Nitrous oxide is commonly used during childbirth and in A&E as pain relief. Please tell the midwife or A&E staff treating you (or ask your family to) that you have gas in your eye and that they should not administer any nitrous oxide. Should you need a general anaesthetic for any reason during this time it is important that you also tell the anaesthetist that you have had surgery and gas in your eye.
This is the hardest part of the recovery following your surgery, but the most important. If we put gas or silicone oil in your eye, we usually ask you to “posture” for up to seven days. This means lying or sitting in a position that keeps your face down (so that the bubble floats up and presses the retina into position while it is healing).
Your surgeon will advise you if it is necessary for you to posture after your surgery, and will give you another information to show you how to do this.
You can self-fund or use private medical insurance to fund your treatment.